{"id":6153,"date":"2023-10-28T01:31:39","date_gmt":"2023-10-28T01:31:39","guid":{"rendered":"https:\/\/introlab.net\/?page_id=6153"},"modified":"2024-03-18T22:12:59","modified_gmt":"2024-03-18T22:12:59","slug":"roma-index","status":"publish","type":"page","link":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/roma-index\/","title":{"rendered":"ROMA index"},"content":{"rendered":"<p>The ROMA index is utilized in <a href=\"https:\/\/staging-introlab.dev-digitaldot.com\/\">IntroLab<\/a> laboratories and offers precise determination of the probability of ovarian malignancy, providing essential information for further treatment and patient monitoring.<!--more--><\/p>\n<h2>What does the ROMA index represent?<\/h2>\n<p>The ROMA index, or the<strong> Risk of Ovarian Malignancy Algorithm<\/strong>, is a mathematical model used to assess the likelihood of ovarian cancer in women. This model is based on measuring the concentration of two blood biomarkers &#8211; HE4 protein and Cancer Antigen 125 (CA 125). Considering a woman&#8217;s menopausal status and these values, t<em>he ROMA index provides an estimation of the risk of ovarian cancer.<\/em> HE4 is a protein that is commonly found in high concentrations in women with epithelial ovarian cancer.<\/p>\n<h2>What is the purpose of measuring the ROMA index?<\/h2>\n<p>The ROMA index serves as a crucial tool in diagnosing and monitoring various diseases, as well as assessing the functionality of vital organs. It is particularly important in the context of epithelial ovarian carcinoma, where the<strong> HE4 protein is used in combination with CA-125<\/strong> to monitor patients who have been treated for this type of cancer. For HE4 to be effective as a tumor marker, its concentration must be elevated before the start of treatment.<\/p>\n<h2>How are the results interpreted?<\/h2>\n<p>Based on the values of the ROMA index, an assessment is made as to whether the patient has ovarian cancer and whether they fall into the low or high-risk group for this disease. The reference interval is indicated on each validated report, and the values vary depending on whether the woman is in the pre or post-menopausal period. <em>An elevated ROMA index value indicates a higher likelihood that the tumor is malignant.<\/em> For pre-menopausal women, the value of this index should be less than 1.14 (indicating a low risk of ovarian malignancy), while for post-menopausal women, the value of this index should be below 2.99 (also indicating a low risk of ovarian malignancy).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The ROMA index is utilized in IntroLab laboratories and offers precise determination of the probability of ovarian malignancy, providing essential information for further treatment and patient monitoring.<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-biohemiska.php","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[203],"tags":[],"class_list":["post-6153","page","type-page","status-publish","hentry","category-immunohemistry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ROMA index | IntroLab Belgrade<\/title>\n<meta name=\"description\" content=\"Visit IntroLab laboratory in Belgrade for the ROMA index analysis. 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