{"id":11740,"date":"2023-07-18T10:43:12","date_gmt":"2023-07-18T10:43:12","guid":{"rendered":"https:\/\/introlab.net\/?page_id=11740"},"modified":"2026-01-22T09:08:06","modified_gmt":"2026-01-22T09:08:06","slug":"ama-anti-mitochondrial-m2-at","status":"publish","type":"page","link":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/ama-anti-mitochondrial-m2-at\/","title":{"rendered":"AMA (Anti-Mitochondrial) M2 At"},"content":{"rendered":"<p>At <a href=\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/\">IntroLab<\/a> in Belgrade, we are dedicated to<strong> delivering accurate and reliable tests<\/strong> crucial for our patients&#8217; health. One important test we offer is the AMA (Anti-Mitochondrial) M2 At analysis, which is vital for identifying and monitoring certain autoimmune diseases. Our mission is to provide clear, precise information and the highest quality service.<\/p>\n<h2>What is AMA (Anti-Mitochondrial) M2 At?<\/h2>\n<p>AMA M2 At, or anti-mitochondrial antibodies type M2, are specific antibodies crucial in certain autoimmune diseases, such as <strong>primary biliary cirrhosis (PBC)<\/strong>. These antibodies attack mitochondria, the cellular organelles responsible for energy production, causing significant cellular damage.<\/p>\n<p>These antibodies are highly specific to mitochondrial enzymes, especially those involved in fatty acid metabolism. This can result in specific metabolic changes in patients with elevated levels of these antibodies. <strong>AMA M2 At can be detected in the blood years before any symptoms of the disease appear<\/strong>, making this test highly valuable for early diagnosis.<\/p>\n<h2>When is the test necessary?<\/h2>\n<p>The AMA M2 At test is usually recommended for individuals exhibiting symptoms of autoimmune diseases, including:<\/p>\n<ul>\n<li>Fatigue<\/li>\n<li>Itchy skin<\/li>\n<li>Jaundice<\/li>\n<li>Discomfort in the upper right abdomen<\/li>\n<\/ul>\n<p>This test is also beneficial for those with a family history of autoimmune diseases.<\/p>\n<h2>Specifics and subtypes of the test<\/h2>\n<p>This test utilizes techniques like<strong> indirect immunofluorescence (IIF) and enzyme-linked immunosorbent assay (ELISA).<\/strong> While these methods are specific and sensitive, they can occasionally yield false-positive or false-negative results. To confirm a diagnosis, repeating the test or conducting additional laboratory analyses may be necessary.<\/p>\n<p>The AMA M2 At test is one type of anti-mitochondrial antibody test. There are several subtypes of AMA antibodies, including <strong>M1, M3, M4, M8, M9<\/strong>, and others. Each subtype has unique specificities and may be linked to different conditions.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>At IntroLab in Belgrade, we are dedicated to delivering accurate and reliable tests crucial for our patients&#8217; health. One important test we offer is the AMA (Anti-Mitochondrial) M2 At analysis, which is vital for identifying and monitoring certain autoimmune diseases. Our mission is to provide clear, precise information and the highest quality service. 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