{"id":11514,"date":"2023-06-18T01:50:23","date_gmt":"2023-06-18T01:50:23","guid":{"rendered":"https:\/\/introlab.net\/?page_id=11514"},"modified":"2026-01-22T07:19:32","modified_gmt":"2026-01-22T07:19:32","slug":"melatonin-in-urine","status":"publish","type":"page","link":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/","title":{"rendered":"Melatonin in Urine"},"content":{"rendered":"<p>Melatonin is a hormone produced by the pineal gland in response to light. It helps<strong> regulate the sleep-wake cycle, known as the circadian rhythm,<\/strong> and functions as a potent antioxidant. Melatonin production peaks at night, with blood levels rising sharply at dusk, leading to feelings of sleepiness. Melatonin is present in urine because it is excreted from the body this way. You can have this test done at<a href=\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/\"> IntroLab<\/a> in Belgrade.<\/p>\n<h2>The Importance of Melatonin<\/h2>\n<p>Melatonin is essential for several vital functions, <em>including protecting the cardiovascular system, regulating endocrine functions, modulating the immune system, and controlling body temperature.<\/em> It also has significant antioxidant properties, stimulates the production of growth hormone, and helps alleviate symptoms of seasonal affective disorder (SAD).<\/p>\n<h2>Melatonin Urine Test<\/h2>\n<p><strong>This test measures the levels of 6-Sulfatoxymelatonin (MT6s),<\/strong> the main metabolite of melatonin, in the urine. While MT6s itself is not physiologically active, its levels in urine reflect the body\u2019s melatonin production. Low urinary MT6s levels may suggest the need for additional melatonin supplementation.<\/p>\n<h2>Clinical Significance<\/h2>\n<p>Low melatonin levels can lead to <em>sleep issues (insomnia or waking during the night), a weakened immune system, mood changes, fatigue, and low growth hormone levels.<\/em> High melatonin levels, on the other hand, can inhibit ovulation in women and lower body temperature.<\/p>\n<p>Melatonin level changes may be linked to:<\/p>\n<ul>\n<li><strong>Sleep disorders<\/strong><\/li>\n<li><strong>Stress<\/strong><\/li>\n<li><strong>Depression<\/strong><\/li>\n<li><strong>Anorexia nervosa<\/strong><\/li>\n<li><strong>Schizophrenia<\/strong><\/li>\n<li><strong>Sexual maturation during puberty<\/strong><\/li>\n<li><strong>Immune disorders<\/strong><\/li>\n<\/ul>\n<h2>Procedure for Measuring Melatonin in Urine<\/h2>\n<p>For a melatonin urine test, <strong>a 20 ml urine sample is required.<\/strong> The samples are extracted and dried under nitrogen before immunoassay. Melatonin levels are measured using a competitive enzyme immunoassay (EIA) with anti-melatonin and biotinylated melatonin.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Melatonin is a hormone produced by the pineal gland in response to light. It helps regulate the sleep-wake cycle, known as the circadian rhythm, and functions as a potent antioxidant. Melatonin production peaks at night, with blood levels rising sharply at dusk, leading to feelings of sleepiness. Melatonin is present in urine because it is [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-biohemiska.php","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[233],"tags":[],"class_list":["post-11514","page","type-page","status-publish","hentry","category-urine-analysis"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Melatonin in Urine | IntroLab Belgrade<\/title>\n<meta name=\"description\" content=\"Suffering from sleep disorders? Get a melatonin in urine test at the renowned laboratory in Belgrade, IntroLab!\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Melatonin in Urine | IntroLab Belgrade\" \/>\n<meta property=\"og:description\" content=\"Suffering from sleep disorders? Get a melatonin in urine test at the renowned laboratory in Belgrade, IntroLab!\" \/>\n<meta property=\"og:url\" content=\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/\" \/>\n<meta property=\"og:site_name\" content=\"Introlab Laboratorija Beograd\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-22T07:19:32+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/\",\"url\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/\",\"name\":\"Melatonin in Urine | IntroLab Belgrade\",\"isPartOf\":{\"@id\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/#website\"},\"datePublished\":\"2023-06-18T01:50:23+00:00\",\"dateModified\":\"2026-01-22T07:19:32+00:00\",\"description\":\"Suffering from sleep disorders? Get a melatonin in urine test at the renowned laboratory in Belgrade, IntroLab!\",\"breadcrumb\":{\"@id\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Melatonin in Urine\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/#website\",\"url\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/\",\"name\":\"Introlab Laboratorija Beograd\",\"description\":\"Dijagnosti\u010dke Analize Krvi\",\"publisher\":{\"@id\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/#organization\",\"name\":\"Introlab Laboratorija Beograd\",\"url\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/staging-introlab.dev-digitaldot.com\/wp-content\/uploads\/2023\/05\/introlablogo-ai.svg\",\"contentUrl\":\"https:\/\/staging-introlab.dev-digitaldot.com\/wp-content\/uploads\/2023\/05\/introlablogo-ai.svg\",\"caption\":\"Introlab Laboratorija Beograd\"},\"image\":{\"@id\":\"https:\/\/staging-introlab.dev-digitaldot.com\/en\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Melatonin in Urine | IntroLab Belgrade","description":"Suffering from sleep disorders? Get a melatonin in urine test at the renowned laboratory in Belgrade, IntroLab!","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/","og_locale":"en_US","og_type":"article","og_title":"Melatonin in Urine | IntroLab Belgrade","og_description":"Suffering from sleep disorders? Get a melatonin in urine test at the renowned laboratory in Belgrade, IntroLab!","og_url":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/","og_site_name":"Introlab Laboratorija Beograd","article_modified_time":"2026-01-22T07:19:32+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/","url":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/","name":"Melatonin in Urine | IntroLab Belgrade","isPartOf":{"@id":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/#website"},"datePublished":"2023-06-18T01:50:23+00:00","dateModified":"2026-01-22T07:19:32+00:00","description":"Suffering from sleep disorders? Get a melatonin in urine test at the renowned laboratory in Belgrade, IntroLab!","breadcrumb":{"@id":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/melatonin-in-urine\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/"},{"@type":"ListItem","position":2,"name":"Melatonin in Urine"}]},{"@type":"WebSite","@id":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/#website","url":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/","name":"Introlab Laboratorija Beograd","description":"Dijagnosti\u010dke Analize Krvi","publisher":{"@id":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/#organization","name":"Introlab Laboratorija Beograd","url":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/#\/schema\/logo\/image\/","url":"https:\/\/staging-introlab.dev-digitaldot.com\/wp-content\/uploads\/2023\/05\/introlablogo-ai.svg","contentUrl":"https:\/\/staging-introlab.dev-digitaldot.com\/wp-content\/uploads\/2023\/05\/introlablogo-ai.svg","caption":"Introlab Laboratorija Beograd"},"image":{"@id":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/#\/schema\/logo\/image\/"}}]}},"_hostinger_reach_plugin_has_subscription_block":false,"_hostinger_reach_plugin_is_elementor":false,"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/wp-json\/wp\/v2\/pages\/11514","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/wp-json\/wp\/v2\/comments?post=11514"}],"version-history":[{"count":1,"href":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/wp-json\/wp\/v2\/pages\/11514\/revisions"}],"predecessor-version":[{"id":17879,"href":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/wp-json\/wp\/v2\/pages\/11514\/revisions\/17879"}],"wp:attachment":[{"href":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/wp-json\/wp\/v2\/media?parent=11514"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/wp-json\/wp\/v2\/categories?post=11514"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/staging-introlab.dev-digitaldot.com\/en\/wp-json\/wp\/v2\/tags?post=11514"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}