SHBG

Sex-hormone binding globulin (SHBG) is an important protein that plays a key role in regulating hormonal balance in the body. At IntroLab, we are dedicated to providing quality analysis to give patients a detailed insight into their hormonal status.

What is SHBG?

Sex-hormone binding globulin is a protein produced in the liver and plays a crucial role in binding and transporting certain sex hormones in the body. It functions as a hormone carrier, regulating their availability and activity in tissues. It binds hormones such as estrogen and testosterone, maintaining hormonal balance and affecting various physiological processes.

When is SHBG analysis performed?

Sex-hormone binding globulin is measured in various situations and indications:

• Hormonal balance assessment: SHBG is often measured as part of a comprehensive hormone analysis to assess the balance of hormones in the body. This can be useful in diagnosing and monitoring hormonal disorders.
• Fertility and reproductive health: Determining SHBG levels can help in assessing fertility, monitoring the menstrual cycle, and evaluating reproductive status.
• Metabolic health assessment: SHBG levels can be related to metabolic health, including glucose and lipid regulation. The analysis can be part of an assessment of the risk of metabolic disorders such as type 2 diabetes and cardiovascular disease.
• Monitoring hormone therapy: In patients undergoing hormone therapy, determining SHBG can be useful for monitoring the effectiveness of therapy and optimizing the dosage of hormonal preparations.

Lowered values

Lowered SHBG levels can be associated with various conditions such as obesity, polycystic ovary syndrome, hyperinsulinemia, or metabolic syndrome. Low values can affect hormonal balance and have effects on fertility, metabolism, and other physiological processes.

Elevated values

Elevated levels can be associated with conditions such as hyperandrogenism, hypothyroidism, or the use of certain medications. High levels can affect the availability of free hormones in the body, which can have effects on reproductive health and hormonal balance.

Preparation for analysis

No special preparation is necessary for SHBG analysis. It is recommended to take a blood sample at the appropriate time interval and to carefully follow the instructions for sample preparation. Our team of experts will provide you with all the necessary information about preparing for the analysis to ensure accurate and reliable results.