Prenatal Next Karyo Plus Test: All Chromosomes + Sex Chromosomes + Deletions and Microdeletions + Gender + Hereditary and Non-Hereditary Diseases in the Baby

Next Karyo Plus is a prenatal test designed for the early detection of genetic disorders in the fetus, based on DNA analysis from the mother’s blood. It is non-invasive, poses no risk to the mother or baby, and can be performed early in pregnancy. In Belgrade, this test is available at IntroLab, a laboratory well-known for its expertise in genetic testing.

What does the Next Karyo Plus test screen for?

The test screens for chromosomal abnormalities in the fetus, including:

• Aneuploidies: These are abnormalities in the number of chromosomes, such as Trisomy 21 (Down syndrome), Trisomy 18 (Edwards syndrome), and Trisomy 13 (Patau syndrome).
• Sex chromosome disorders: These are disorders related to the X and Y chromosomes, such as Turner syndrome, Klinefelter syndrome, and others.
• Microdeletion syndromes: These are syndromes caused by small losses of genetic material in the chromosomes, such as DiGeorge syndrome.

How is sampling for the Next Karyo Plus test performed?

The sampling process is straightforward and non-invasive. The Next Karyo Plus test utilizes NGS technology to accurately detect genetic abnormalities. A blood sample is drawn from the pregnant woman and sent to the laboratory for analysis. This test can be performed as early as the 10th week of pregnancy, allowing for early detection of potential genetic disorders.

How accurate is the Next Karyo Plus test?

The test is highly accurate, with a strong detection rate for most of the chromosomal disorders it covers. While the test is very reliable, if a positive result is found, additional testing, such as amniocentesis, is often recommended to confirm the results.

What are sex chromosome disorders?

Sex chromosome disorders are abnormalities that affect the X and Y chromosomes, which determine the sex of the fetus. These disorders can include:

• Turner Syndrome (45,X): The absence of one X chromosome in girls.
• Klinefelter Syndrome (47,XXY): The presence of an extra X chromosome in boys.
• Triple X Syndrome (47,XXX): The presence of an extra X chromosome in girls.
• Jacob’s Syndrome (47,XYY): The presence of an extra Y chromosome in boys.

What are aneuploidies?

Aneuploidies are chromosomal abnormalities that involve changes in the number of chromosomes. Common aneuploidies detected by the Next Karyo Plus test include:

• Trisomy 21 (Down Syndrome): The presence of an extra chromosome 21.
• Trisomy 18 (Edwards Syndrome): The presence of an extra chromosome 18.
• Trisomy 13 (Patau Syndrome): The presence of an extra chromosome 13.

What are microdeletion syndromes?

Microdeletion syndromes are genetic disorders caused by the loss of a small segment of a chromosome. The Next Karyo Plus test can detect several significant microdeletion syndromes, including:

• DiGeorge Syndrome: The loss of genetic material on chromosome 22.
• Prader-Willi Syndrome: The loss of genetic material on chromosome 15.
• Angelman Syndrome: Similar to Prader-Willi Syndrome but with different clinical manifestations.

What is the price of the Next Karyo plus test?

The price of the Next Karyo Plus test is 153,282 RSD. For more information and to schedule an appointment, please contact IntroLab.

Prenatal tests and genetic panels at IntroLab

In addition to the Next Karyo Plus test, IntroLab in Belgrade offers a wide range of other prenatal tests and genetic panels for a comprehensive analysis of genetic health.

Available prenatal tests include:

• Prenatal BASIC Test
• Prenatal PLUS Test
• Prenatal EXPERT Test
• Prenatal PREMIUM Test
• Prenatal SPECIAL Test
• Prenatal SPECIAL + SMA Test
• Prenatal Next Karyo Plus Test
• Prenatal Next Karyo Full Test

Beyond prenatal tests, IntroLab also provides specialized genetic panels that offer detailed analysis of various hereditary disorders.

• Autoinflammatory diseases panel
• Cardiomyopathy panel
• Arrhythmia panel
• Marfan syndrome panel
• Epilepsy panel
• Clinical exome sequencing
• Molecular karyotyping

These tests and panels use advanced NGS technology for precise analysis, offering crucial information necessary for making informed decisions about further medical care and treatment.