Prenatal BASIC Test: T 21, 18, 13 + Gender

The BASIC prenatal test, offered at IntroLab in Belgrade, is a non-invasive prenatal test used for the early detection of the most common chromosomal abnormalities and for determining the baby’s gender. This test is straightforward, safe, and provides crucial information about the fetus’s health.

How is the BASIC test conducted?

The BASIC test is performed using a blood sample from the pregnant woman. During pregnancy, small fragments of fetal DNA circulate in the mother’s blood. This sample is analyzed to identify specific genetic information about the fetus. The analysis uses NGS technology, which allows for the highly accurate detection of genetic abnormalities. The procedure is non-invasive, meaning there is no risk to the mother or baby, and it can be performed as early as the 10th week of pregnancy. The blood sample is collected just like a standard blood test and then sent to the laboratory for analysis.

What does the test detect?

The BASIC test identifies the most common chromosomal abnormalities and determines the baby’s gender. It detects the following:

• Trisomy 21 (Down Syndrome): Caused by an extra chromosome 21, this condition can lead to intellectual disabilities and physical abnormalities.
• Trisomy 18 (Edwards Syndrome): A rare disorder resulting from an extra chromosome 18, which can cause severe physical and intellectual disabilities, with a high mortality rate in early childhood.
• Trisomy 13 (Patau Syndrome): This disorder, caused by an extra chromosome 13, is associated with serious health issues and physical malformations.
• Baby’s Gender: The BASIC test also accurately determines whether the pregnant woman is carrying a boy or a girl.

How are test results interpreted?

The results of the BASIC test provide information about the presence or absence of chromosomal abnormalities and the baby’s gender:

• Negative Result (Low Risk): Indicates that no chromosomal abnormalities were detected in the fetus. This result suggests a low risk of trisomies but cannot guarantee the complete absence of all possible genetic disorders.
• Positive Result (High Risk): Indicates the presence of a chromosomal abnormality, such as trisomy 21, 18, or 13. If the result is positive, additional diagnostic tests, such as amniocentesis, are recommended to confirm the finding.
• Baby’s Gender: Information about the baby’s gender is included in the results and can be shared with the expectant mother if she wishes to know.

Why are prenatal tests important?

Prenatal tests provide essential information about your baby’s health early in pregnancy. These tests help identify potential genetic abnormalities that could impact the baby’s development and well-being. Early detection allows parents to prepare for the birth of a child with special needs, explore treatment options, or make informed decisions about the pregnancy.

Why should I choose prenatal testing?

Opting for prenatal tests, like the BASIC test, provides you with early information about your baby’s health without any risk to you or your baby. The test is non-invasive, straightforward, and offers highly accurate detection of the most common chromosomal disorders. This information can be vital for planning prenatal care and preparing for the arrival of your new family member.

Additional prenatal options

In addition to the BASIC test, IntroLab offers other prenatal tests for pregnant women seeking more comprehensive screening:

• PLUS test: This test includes all the analyses from the BASIC test, plus additional testing for sex chromosomes. The PLUS test provides deeper insights into the baby’s genetic health and can detect additional chromosomal abnormalities.
• EXPERT test: The EXPERT test includes analysis for trisomies and sex chromosomes, as well as microdeletions like those associated with DiGeorge syndrome. This test offers a broader spectrum of genetic information and is ideal for pregnant women seeking a more detailed risk assessment.
• PREMIUM test: The PREMIUM test is the most comprehensive, including analysis of all chromosomes, sex chromosomes, microdeletions, and determining the baby’s gender. It also includes screening for 100 hereditary and monogenic diseases. This test is perfect for pregnant women who want the highest level of assurance and detailed information on potential genetic risks.
• ALL CHROMOSOMES test: This test offers a complete analysis of all chromosomes, including sex chromosomes, deletions, and microdeletions, along with determining the baby’s gender.
• SPECIAL test: The SPECIAL test covers the most significant chromosomal abnormalities, microdeletions, and an additional 100 hereditary diseases, providing a comprehensive genetic assessment.
• SPECIAL + SMA test: An extended version of the SPECIAL test, this option also includes analysis for SMA (spinal muscular atrophy) and 100 monogenic diseases, offering extra peace of mind.

Specialized genetic panels

Along with prenatal tests, IntroLab offers specialized genetic panels that provide detailed information on various genetic conditions and disorders:

• Autoinflammatory diseases panel
• Cardiomyopathy panel
• Arrhythmia panel
• Marfan syndrome panel
• Epilepsy panel
• Clinical exome sequencing
• Molecular karyotyping

These genetic panels deliver a broad spectrum of information crucial for making informed decisions during pregnancy, enabling doctors and parents to plan further care and procedures with a high degree of confidence.