Molecular Karyotype

In modern genetics, molecular karyotyping represents a significant advancement in the diagnosis of genetic disorders. Traditional karyotyping allows for the examination of chromosomes under a microscope, but it has limited resolution and cannot detect small structural changes at the DNA level. Molecular karyotyping, also known as microarray test, uses advanced technologies to provide a more detailed view of chromosomal structures. At the IntroLab in Belgrade, we provide precise and reliable molecular karyotyping services, which are crucial for the accurate diagnosis of various genetic conditions. This can aid in the early detection and better understanding of complex genetic disorders.

What is molecular karyotype?

Molecular karyotype is an advanced genetic technique that allows for detailed examination of chromosomes at the DNA level. This test can detect subtle changes in chromosome structure, such as deletions or duplications of small DNA segments, which are not visible with traditional karyotyping.

Who is recommended for molecular karyotype?

This test is recommended for individuals with suspected genetic disorders, including developmental and intellectual disabilities, congenital anomalies, as well as couples with a history of infertility or recurrent miscarriages. It is also used in prenatal testing when specific risk factors are present.

How is molecular karyotype test performed?

Molecular karyotype test is performed by taking a sample of blood or other tissue. DNA is extracted from the cells of the sample and hybridized on microarray chips containing millions of small DNA probes. These probes can detect the presence or absence of specific DNA segments, allowing the identification of chromosomal abnormalities.