MxA/CRP Test | IntroLab Belgrade

Exclusive in Serbia: MxA/CRP Test to Differentiate Between Viral and Bacterial Infections

Updated:

March 31, 2025

Published:

February 10, 2025

Reading Time:

7 min

Acute respiratory infections like the flu or common cold often come with similar symptoms – fever, cough, nasal congestion, and sore or dry throat. But one key question remains: is the infection viral or bacterial? The answer can make the difference between proper treatment and unnecessary antibiotic use. For the first time in Serbia, the MxA/CRP test offers a fast and reliable way to determine the nature of an infection – delivering results in just 12 minutes from a simple fingertip blood sample. It helps doctors make the best possible decision regarding treatment. Don’t waste time – schedule your test at IntroLab Laboratory in Belgrade and get a reliable answer!

Why Is It Important to Differentiate Between Viral and Bacterial Infections?

Respiratory infections often come with similar symptoms, such as fever, cough, runny nose, and sore throat. However, their causes can be completely different – which means the treatment approach must differ as well.

Viral Infections

Understanding viral infections helps avoid the unnecessary use of antibiotics and ensures the application of appropriate treatment.

  • Cause: Triggered by viruses such as influenza, the common cold, RSV, and other respiratory viruses.
  • Treatment: Antibiotics are not effective against viruses, as they target bacteria only. Treatment focuses on relieving symptoms – rest, fluids, fever-reducing medications, and symptom-specific remedies.
  • Duration: Usually resolve on their own within a few days to two weeks, depending on the virus type and the immune response.
  • Complications: In rare cases, viral infections can lead to secondary bacterial infections, such as pneumonia or sinusitis.
Fingerstick Blood Sample
MxA/CRP Test – Fast and accurate differentiation between viral and bacterial infections.

Bacterial Infections

A proper approach to treating bacterial infections can prevent serious complications and support faster recovery.

  • Cause: Caused by bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, and other pathogenic bacteria.
  • Treatment: Unlike viral infections, bacterial infections may require antibiotics to stop the spread and prevent complications. The appropriate antibiotic depends on the type of bacteria and the severity of the infection.
  • Duration: Without proper treatment, bacterial infections can last longer and worsen, potentially leading to more serious health issues.
  • Complications: If not recognized and treated in time, they can result in serious outcomes such as bacterial pneumonia, meningitis, or sepsis.

Why Is Timely Diagnosis Crucial?

Quick identification of the infection allows doctors to make the right treatment decision, reducing the risk of unnecessary antibiotic use and potential complications.

A misdiagnosis can lead to inadequate treatment, increase the risk of antibiotic resistance, and prolong recovery time. On the other hand, an undetected bacterial infection can worsen and require longer, more aggressive therapy.

Thanks to the MxA/CRP test, it is now possible to quickly and accurately determine whether an infection is viral or bacterial in origin.

How Does the MxA/CRP Test Work?

CRP and MxA markers work together to identify the type of respiratory infection, which is essential for choosing the right treatment. The test quickly and reliably determines whether an infection is viral or bacterial – enabling fast and accurate diagnosis and helping doctors decide if antibiotics are truly necessary.

MxA – Marker of Viral Infections

MxA (myxovirus resistance protein A) is an intracellular blood protein involved in cellular resistance against a broad range of viruses. Its levels increase in the presence of most acute viral infections. MxA is produced by the body’s immune cells – especially interferons – in response to viral activity. It plays a key role in defending the body by inhibiting viral replication inside infected cells.

The MxA test is primarily used to detect viral infections. It helps distinguish between viral and bacterial infections, as MxA levels rise significantly during viral illness. When the body is infected by a virus, cells release interferons, which in turn stimulate the production of MxA protein. The test measures the concentration of MxA in the blood, offering insight into the cause of the infection.

Interpretation:

  • High MxA levels: Typically indicate a viral infection, as MxA is produced in response to viral triggers.
  • Low or normal MxA levels: Suggest that a viral infection is unlikely, and the illness may be caused by a non-viral source.

CRP – Marker of Inflammatory Processes

CRP (C-reactive protein) is a protein produced by the liver in response to inflammation. It is an acute-phase protein, meaning its levels rise quickly when the body reacts to infection, injury, or any condition that triggers inflammation. When inflammation is present, the liver increases CRP production. The CRP test measures the concentration of this protein in the blood – higher levels indicate a stronger inflammatory response.

Interpretation:

  • Low CRP levels: Considered normal and suggest no significant inflammation.
  • Elevated CRP levels: Indicate the presence of inflammation or infection but do not specify the exact cause.

CRP levels are also used to monitor the effectiveness of treatment for inflammatory conditions. In the context of infection, CRP tends to rise more significantly in bacterial infections than in viral ones.

A lab technician collecting a small blood sample from the fingertip for the MxA/CRP test
Don’t guess – Identify the cause of infection quickly and reliably.

How Is the MxA/CRP Test Performed?

The test is performed by taking a small blood sample from the fingertip, making it suitable for patients of all ages – including young children. Within just 12 minutes, the analysis reveals MxA and CRP protein levels, allowing doctors to make an informed decision about treatment.

MxA/CRP Test Compared to Standard Laboratory Analyses

When diagnosing infections, both accuracy and speed are crucial for effective treatment. The MxA/CRP test offers a significant advantage over traditional laboratory methods.

  • Standard tests (CBC, white blood cell count, sedimentation rate (ESR), standalone CRP) can indicate inflammation, but they do not clearly distinguish between viral and bacterial infections.
  • The MxA/CRP test provides a clear differentiation within just 12 minutes – eliminating the wait for extended lab results.

Who Benefits Most from the Test?

The MxA/CRP test is especially useful for the following groups:

  • Children: Since respiratory infections are common in children, this test helps distinguish between viral and bacterial causes, reducing unnecessary antibiotic use.
  • People with weakened immune systems: Individuals with chronic illnesses or compromised immunity can quickly find out whether antibiotic therapy is needed.
  • Older adults: Accurate diagnosis helps prevent complications and enables timely treatment in higher-risk patients.
  • Anyone with infection symptoms: If you have a fever, cough, nasal congestion, and are unsure whether you need antibiotics, this test offers a reliable answer.
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Frequently Asked Questions

  • How much does the test cost? The price of the MxA/CRP test is 1100 RSD.
  • Can I take the test if I’m already on antibiotics? Yes, but antibiotics may affect the results. It’s best to consult your doctor before testing.
  • Do I need to fast before the test? No, the test can be done at any time of day without special preparation.
  • Is the test suitable for children? Yes, the test is completely safe and non-invasive, making it suitable even for children.
  • Can multiple family members be tested at the same time? Yes, several family members can be tested at once without extra waiting time.
  • How often can I take this test? You can take the test as needed, especially if new symptoms appear or to monitor the course of an infection.

MxA/CRP Test: The First Step Toward More Effective Treatment

The MxA/CRP test is transforming the diagnosis of respiratory infections by giving patients a fast and accurate assessment of their condition – and providing doctors with a reliable tool for making treatment decisions. Timely and precise diagnosis helps reduce unnecessary antibiotic use and improves infection control.

This test is now available exclusively at IntroLab in Belgrade. Schedule your test or visit us to find out if you really need antibiotics!