Double test 2

The double test and triple test are two different prenatal screening tests used to assess the risk of certain chromosomal disorders in pregnant women. IntroLab is a leading laboratory in Belgrade, where, in addition to the standard double test, the triple blood test is also available. Moreover, the cost of the double test in our lab is competitive and affordable.

Difference between the double test and the triple test

The double test is an older form of prenatal screening. It combines the measurement of two biomarkers—free beta-hCG (human chorionic gonadotropin) and PAPP-A (pregnancy-associated plasma protein A). These biomarkers are analyzed in the mother’s blood, and based on their values, the risk for trisomies 21, 18, and 13 (Down syndrome, Edwards syndrome, and Patau syndrome) is assessed.

The triple test is an advanced version of prenatal screening that includes additional biomarkers, such as alpha-fetoprotein (AFP), free estriol (uE3), and inhibin A. These additional biomarkers are also measured in the blood and contribute to a more accurate risk assessment for chromosomal disorders.

The difference between the double and triple test lies in the number of biomarkers analyzed and used to assess the risk of chromosomal disorders. The triple test provides additional information that can improve the accuracy of risk assessment and allow for more precise diagnostics. It is always recommended to consult with a doctor or gynecologist to select the appropriate blood test based on the individual needs and risks of the pregnant woman.

When is the triple blood test needed?

The triple test can be performed for:

• Pregnant women over the age of 35: Maternal age is a risk factor for chromosomal disorders in the baby, so the triple test is recommended to assess the risk in such cases.
• Previously noted abnormalities on an ultrasound: If a previous ultrasound showed possible fetal abnormalities, the triple test could be used as an additional diagnostic method for risk assessment.
• Family history of chromosomal disorders: If there is a family history of chromosomal disorders, the triple test can help assess the risk and detect possible abnormalities early.
• Previous pregnancy with a chromosomal disorder: If the woman had a previous pregnancy with a chromosomal disorder, the triple test could be used to assess the risk in the current pregnancy.
• Personal choice: The triple test can be offered to pregnant women who wish to receive additional information about the risk of chromosomal disorders, even if specific indications are not present.