Anti-gliadin IgA

The anti-gliadin IgA test is an enzyme-linked immunosorbent assay (ELISA) used to detect gluten intolerance by identifying IgA antibodies in human serum. This test is utilized to assess gluten sensitivity in individuals and is offered by the private laboratory IntroLab in Belgrade.

Why is the anti-gliadin IgA test performed?

This test is conducted to diagnose gluten-sensitive enteropathy, commonly known as celiac disease, or dermatitis herpetiformis. A positive result indicates the presence of IgA antibodies, which may suggest the presence of these conditions.

What are the indications for the test?

Indications for this test include symptoms that suggest gluten intolerance, as well as monitoring the effects of a gluten-free diet.

What are the symptoms of gluten intolerance?

Gluten intolerance can cause a wide range of symptoms. Here are some of the most common ones:

• Bloating
• Diarrhea, constipation, and foul-smelling stools
• Abdominal pain
• Headaches and migraines
• Fatigue
• Skin problems
• Depression
• Unexplained weight loss
• Iron-deficiency anemia
• Anxiety
• Autoimmune disorders
• Joint and muscle pain
• Numbness in the legs or arms
• Difficulty thinking clearly (brain fog)

How is the sample collected?

A blood sample is required for this test. It is recommended that the blood is drawn from a vein in the forearm.

Interpretation of results

The results can be categorized as follows:

• Negative: 0-14 U/mL
• Positive: 15 U/mL or higher

What to do after a positive result?

After receiving a positive result, it’s essential to consult with your doctor to understand its implications for your health. If gluten intolerance is confirmed, your doctor or a nutritionist will guide you in developing a diet plan that eliminates gluten. Monitoring your symptoms after making dietary changes is important to determine if they improve, which will help evaluate the diet’s effectiveness and guide further treatment.

Regular follow-up and retesting are recommended after a positive IgA antibody test to monitor progress and therapy effectiveness. Additionally, there are numerous support groups and educational resources available for those with gluten intolerance. Connecting with these resources can help you adjust your lifestyle more effectively.

Disease prevention

Preventing the disease involves eliminating gluten from the diet. Those diagnosed with celiac disease or other gluten-related disorders should follow a strict gluten-free diet.

Analysis details

IgA antibodies are more specific but less sensitive compared to IgG antibodies. Since IgA deficiency is relatively common in patients with celiac disease, using both IgA and IgG antibody tests is recommended for a more accurate diagnosis.

Subtypes of the anti-gliadin IgA test

In addition to the anti-gliadin IgA test, related tests include the Anti-gliadin IgG test.