Glucose-6-phosphate dehydrogenase

Glucose-6-phosphate dehydrogenase is an enzyme that plays a vital role in maintaining the health of red blood cells. A deficiency in G6PD can lead to a condition known as G6PD deficiency, which can cause hemolytic anemia – a condition where red blood cells do not survive as long as they should. Therefore, a Glucose-6-phosphate dehydrogenase analysis at IntroLab laboratory in Belgrade can be of significant benefit to your health!

G6PD deficiency

The most widespread inherited hemolytic anemia occurs due to reduced activity of the G6PD enzyme within red blood cells. Acute hemolysis, caused by G6PD deficiency, often occurs among Mediterranean peoples (5-40%) and among the African American and African populations (2-13%). The G6PD gene is located on the X chromosome, which means the disease is transmitted through X-linked inheritance. Women can be heterozygous or homozygous carriers of this abnormality. On the other hand, men can be either homozygous or completely without this deficit. The G6PD enzyme plays a crucial role in the process of oxidative glycolysis in red blood cells.

Glucose-6-phosphate dehydrogenase analysis – Indications

A blood draw for Glucose-6-phosphate dehydrogenase analysis is necessary if you have symptoms that might indicate G6PD deficiency. Some of these symptoms include:

• Fatigue
• Paleness
• Rapid or labored breathing
• Rapid heart rate
• Dark-colored urine
• Enlarged spleen
• Jaundice.

Blood analysis to detect the level of this enzyme may also be recommended if you are exposed to certain medications or chemicals that can induce hemolytic anemia in people with G6PD deficiency.

For all your Glucose-6-phosphate dehydrogenase analysis needs in Belgrade, you can rely on IntroLab. Contact us today and get your analysis done. Our goal is to provide you with the information you need to understand your health and take steps to improve it.