Lupus Cell

The lupus cell test is a diagnostic tool used in laboratories around the world, including the reputable IntroLab in Belgrade, to detect the presence of antinuclear antibodies and evaluate the autoimmune disease known as systemic lupus erythematosus.

What is systemic lupus erythematosus?

Systemic lupus erythematosus (lupus) is a chronic autoimmune disease that can affect various organs and tissues in the body. Lupus cells, also known as LE cells, are present in the blood of patients with lupus. They have specific characteristics that can be identified through immunological blood tests.

Although the symptoms of lupus can vary from person to person, some common symptoms include:

• Intense fatigue that persists even after rest.
• Joint and muscle pain, which can be diffuse or localized.
• Various types of skin rashes, such as red spots, sensitive skin, a distinctive facial rash (commonly referred to as a butterfly rash across the nose and cheeks), or rashes on other parts of the body.
• Sensitivity to sunlight.
• Kidney problems. Lupus can affect the kidneys, causing symptoms such as leg swelling, high blood pressure, or changes in urine.
• Heart and lung issues. Individuals with lupus may experience chest pain, shortness of breath, or inflammation of the heart’s membranes.
• Digestive system problems. Common issues include loss of appetite, nausea, abdominal pain, or diarrhea.
• Neurological problems. In some cases, lupus can affect the central nervous system, leading to symptoms such as headaches, depression, anxiety, or mood disorders.

When is the lupus cell test performed?

Detecting lupus cells can be useful for diagnosing systemic lupus erythematosus and can also help monitor disease activity over time. The presence of these cells may indicate inflammation and an autoimmune response that is characteristic of this condition.

What does the test involve?

At our Belgrade laboratory, we perform the lupus cell test using immunofluorescence techniques. In this test, a patient’s blood sample is treated with specific substances that bind to antinuclear antibodies, if present. The sample is then observed under a microscope to determine the presence of LE cells.

It is important to note that the lupus cell test is only one of the diagnostic tools used alongside clinical assessments and other laboratory tests to establish a definitive diagnosis. Qualified specialists at IntroLab and physicians conduct this test to provide an accurate diagnosis and appropriate treatment for patients with symptoms of this complex autoimmune disease.