C4 Complement

The C4 complement test is a key test used to determine the concentration or activity of the C4 protein in the blood. Together with the C3 component, C4 plays a vital role in the complement system. Testing for C4 and C3 complements is crucial for assessing immune function, detecting, and monitoring the causes of frequent infections, autoimmune disorders, and other systemic diseases. At IntroLab Belgrade, we offer accurate testing of these proteins to evaluate the health of your immune system.

What is C4 Complement?

C4 complement is an important component of the complement system. Measuring its levels can be helpful in diagnosing acute phase reactions, certain cancers, systemic lupus, immune complex diseases, and other conditions. High levels typically indicate inflammation, while low levels may suggest congenital deficiencies or specific diseases. The complement system plays a critical role in the immune system, protecting the body from pathogens and damaged cells. Disruptions in its function can result in various health issues.

Indications for testing

C4 complement protein testing is vital for evaluating immune system health and diagnosing various conditions. This test is recommended for:

• Diagnosing and monitoring autoimmune diseases such as SLE, angioedema, and rheumatoid arthritis
• Detecting immunodeficiencies that result in recurrent infections
• Tracking chronic infections, inflammatory conditions, and liver or kidney diseases

Symptoms like inflammation, swelling, skin redness, rashes, mouth ulcers, fatigue, and organ dysfunction may be associated with abnormal C4 complement levels. Therefore, this blood test is important if any of these symptoms are present.