ASTO

The ASTO – Anti Streptolysin O test, available at IntroLab in Belgrade, is a diagnostic tool used to detect antibodies generated in response to an infection by the Streptococcus pyogenes bacteria. This test is essential for diagnosing and tracking diseases linked to this bacterium, such as rheumatic fever and strep throat.

What is ASTO – Anti Streptolysin O?

Anti Streptolysin O (ASTO) antibodies are produced by the immune system in response to streptolysin O, a toxin released by Streptococcus pyogenes. This bacterium is a common cause of strep throat and can lead to more severe conditions like rheumatic fever.

Why is it performed and who should be tested?

The ASTO test is typically recommended for individuals exhibiting symptoms of a streptococcal infection, such as:

• Sore throat
• Fever
• Rash
• Joint pain

This test is especially valuable for identifying rheumatic fever, a condition that can occur following an untreated streptococcal infection. Additionally, it can be used to monitor the effectiveness of treatment for streptococcal infections.

How are the results interpreted?

High levels of ASTO antibodies suggest a recent streptococcal infection. However, these results alone cannot determine whether the person is currently ill or if the infection happened in the past. The doctor will interpret the results alongside the patient’s symptoms and other diagnostic tests.

Preparation for the test

No specific preparation is needed for this test. Patients can eat and drink as usual before the test unless the doctor advises otherwise.

Specifics and types of ASTO Testing

Several methods are used to detect ASTO, including hemagglutination, neutralization, and ELISA tests. These techniques are highly specific and capable of detecting even small amounts of antibodies. The selection of a method depends on the laboratory’s protocols and available resources.