Porphyrins in 24-hour urine

Porphyirin is one of the fundamental biomolecules that can provide valuable insights into your health under laboratory conditions. Our laboratory, IntroLab in Belgrade, offers porphyrin analysis in urine to assist in the detection and interpretation of important medical conditions.

What is porphyrin?

Porphyrins are molecules naturally produced in the human body that play a key role in forming hemoglobin, the essential protein in red blood cells responsible for transporting oxygen throughout the body. Porphyrins are generated in the bone marrow and liver and are usually excreted from the body through stool and urine.

Why are porphyrins measured in urine?

Porphyrins in urine are measured for several reasons. The amount and type of porphyrins in urine can indicate the presence of porphyria, a rare group of genetic diseases characterized by excessive accumulation of porphyrins or their precursors in the body. Additionally, the test can be useful in diagnosing other conditions, such as anemia or certain types of cancer.

When are porphyrins measured in urine?

Testing for porphyrins in urine is typically recommended for individuals who exhibit symptoms that may indicate porphyria, including:

• abdominal pain
• changes in mental state
• skin changes

Additionally, the test may be recommended as part of a comprehensive liver health evaluation or if there is suspicion of exposure to certain toxins or medications that can affect porphyrin metabolism.

Subtypes of analysis

There are different subtypes of porphyrin analysis in urine, including total porphyrins, free porphyrins, and bound porphyrins. These various analyses can provide additional information that may help doctors better understand your specific situation.