Vitamin C

Vitamin C, or L-ascorbic acid, is a water-soluble vitamin found in some foods, added to others, and available as a dietary supplement. Since humans cannot produce vitamin C on their own, it is an essential dietary element. Therefore, vitamin C analysis is of great importance, as it can help detect lowered levels of this vitamin. IntroLab laboratory in Belgrade is available for this and other blood analyses for vitamins and minerals.

Importance of Vitamin C

This vitamin is necessary for the production of collagen, L-carnitine, and certain neurotransmitters and is involved in protein metabolism. Collagen is a key component of connective tissue, which is vital for wound healing processes. Vitamin C is also an essential antioxidant that regenerates other antioxidants in the body, including alpha-tocopherol (vitamin E). Besides its biosynthetic and antioxidative functions, vitamin C plays a significant role in immune function and helps in the absorption of non-heme iron, the form of iron present in plant foods.

Where is Vitamin C found?

The best sources of vitamin C are fruits and vegetables such as citrus, tomatoes, potatoes, red and green peppers, kiwis, broccoli, strawberries, Brussels sprouts, and melons. Vitamin C in food can be reduced by long-term storage and cooking, as ascorbic acid is water-soluble and easily destroyed by heat. Steaming or microwave cooking can reduce the loss of vitamin C.

Vitamin C deficiency as an indication for analysis

Insufficient intake of vitamin C leads to scurvy. Symptoms can occur within a month of reduced or no intake of vitamin C. Initial symptoms may include fatigue, lethargy, and gum inflammation. As the deficiency of vitamin C progresses, collagen synthesis becomes impaired, and connective tissues weakened, causing petechiae, joint pains, poor wound healing, and hyperkeratosis. Additional signs of scurvy include depression, as well as swollen and bleeding gums, and weakening or loss of teeth due to weakened tissues and capillary fragility. Iron-deficiency anemia can also occur due to increased bleeding and secondarily reduced iron absorption due to low intake of this vitamin. In children, bone disease may be present. If untreated, scurvy is fatal.

When is there an increased need for this vitamin?

The need for vitamin C may increase due to the use of aspirin, oral contraceptive pills, tetracyclines, and many other medications. Psychological stress and aging also tend to increase the need for vitamin C.

How is sampling for vitamin C analysis performed?

At IntroLab, vitamin C analysis is performed to assess deficiency. Vitamin C should be measured in blood samples taken after a period of overnight fasting. Samples must not be hemolyzed and must be protected from light.